Systematic Review and Meta-analysis of Prevalence of Coronary

Studies have reported varied prevalence estimates of coronary Background artery disease (CAD) in cardiac myxoma patients. We performed a systematic review and meta-analysis of observational studies to summarize the point prevalence of CAD in adults with cardiac myxomas. : Two independent investigators searched MEDLINE Methods and Results and LILACS databases using the terms " ”, " " Myxoma Coronary Angiography and " " from inception through December 2014 for all relevant Coronary Disease studies. We included 6 observational studies. Publication bias was evaluated through Egger's test and Trim and Fill method. A pooled estimate of CAD prevalence with corresponding 95% confidence interval (CI) was calculated based on a random-effects model. The pooled CAD prevalence in adult cardiac myxoma patients was 20.7% with low heterogeneity (I = 14.86%). : It is a matter of debate if preoperative coronary angiography Conclusions must be done as a routine procedure. Although coronary disease and angiographically detectable neovascularity can alter surgical management, more studies are needed to evaluate this question. Matheus Silva ( ) Corresponding author: [email protected] Competing interests: No competing interests were disclosed. Silva M, Carneiro M, Nunes J How to cite this article: et al. Systematic Review and Meta-analysis of Prevalence of Coronary Artery 2015, :194 (doi: Disease in Adult Patients with Cardiac Myxomas [version 1; referees: 2 approved] F1000Research 4 ) 10.12688/f1000research.6641.1 © 2015 Silva M . This is an open access article distributed under the terms of the , which Copyright: et al Creative Commons Attribution Licence permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Data associated with the article are available under the terms of the (CC0 1.0 Public domain dedication). Creative Commons Zero "No rights reserved" data waiver The authors declared that no grants were involved in supporting this work. Grant information: 07 Jul 2015, :194 (doi: ) First published: 4 10.12688/f1000research.6641.1 1 2 2 2